Recently Fast dissolving oral drug delivery systems are the most advanced form of oral solid dosage form due to more flexibility and comfort. It improve the efficacy of active pharmaceutical ingredients by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. Traditional tablets and capsules administered with an 8-oz. glass of water may be inconvenient or impractical for some patients. For example, a very elderly patient may not be able to swallow a daily dose of antidepressant. An eight year- old with allergies could use a more convenient dosage form than antihistaminic syrup. A schizophrenic patient in the institutional setting can hide a conventional tablet under his or her tongue to avoid their daily dose of an atypical antipsychotic. For these complications the new approach may be convenient for patients.